1. (6 points) A diploid cell contains three pairs of homologous chromosomesdesignated C1 and C2, M1 and M2, and S1 and S2. No crossing over occurs.a. What combination(s) of chromosomes are possible in daughter cells followingmitosis?In mitosis, two genetically identical daughter cells are produced. Therefore, theonly possible combination of chromosomes is C1/C2/M1/M2/S1/S2 since allgenetic material is inherited.b. What combination(s) of chromosomes are possible in haploid cells followingboth divisions of meiosis? (Hint: remember independent assortment)C1/M1/S1, C1/M1/S2, C2/M1/S1, C1/M2/S1, C1/M2/S2, C2/M1/S1, C2/M2/S1or C2/M2/S2.2. (15 points) A recessive mutant allele, black, causes a very dark body inDrosophila when homozygous. The normal wild-type color is gray.a. A black female is crossed to a heterozygous gray male. What are the parentalgenotypes?b. What F1 phenotypic and genotypic ratios are produced from this cross? (Showyour Punnett Square)3. (9 points) R codes for red flower color and r codes for white flower color.a. What color would Rr be if R has complete dominance?b. What color would Rr be if R and r are codominant?c. What color would Rr be if R has incomplete dominance?4. (15 points) Red-green colorblindness is an X-linked recessive mutation. Acolorblind female is crossed with a normal male.a. What are the parental genotypes? (Hint: the sex of the parent is important)?SC435: Geneticsb. Diagram the F1 results from this cross. (Show your Punnett Square).c. Diagram the F2 results. (Show your Punnett Square).5.(5 points) In a dihybrid cross between RrTt and RRtt, what are the genotypeand phenotype ratios of the offspring, assuming R and T are dominant? Rcodes for round seed, while r codes for wrinkled seed. T codes for tall height,while t codes for short height. (Show your Punnett Square).6. (15 points) The pedigree below traces the inheritance of alkaptonuria, abiochemical disorder. Affected individuals, indicated here by the filled-in circlesand squares, are unable to break down a substance called alkapton, whichcolors the urine and stains body tissues.a. Does alkaptonuria appear to be caused by a dominant or recessive allele?Explain.Alkaptonuria appears to be caused by a recessive allele because Ann andMichael do not have the disorder but their child, Carla, does. Ann andMichael must be carrying the recessive allele but it is masked by thedominant oneb. What is George?s phenotype?George is Aa, since some of his children with Arlene are affectedc. Is it possible for Daniel to have a child with alkaptonuria? Explain.Yes Christopher can have the AA or Aa genotype.?SC435: Geneticsd. How would knowing the pattern of inheritance influence the treatment planfor this disease?It would provide guidance to determine if genetic testing is appropriate.7. (10 points) Mary has type A blood and her husband has type B blood. Herhusband?s parents both had type AB. They have three children, one with type A,one with type AB, and one with type B. Relatives suspect that one of the childrenwas adopted.a. What are the parent?s blood genotypes?b. Which child was adopted? Explain your answer.
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